If you're an open-source advocate or part of a privacy-conscious team, Penpot is the right choice. Its self-hostable nature and adherence to open standards ensure that your design processes remain private and secure. However, if you need access to a robust ecosystem of plugins and polished performance, you'll likely find Penpot lacking, making it less suitable for teams that require a highly refined tool like Figma.
On the other hand, if you're a designer or founder looking to create and publish interactive marketing sites or portfolios without diving into code, Framer is ideal. Its strengths lie in delivering seamless animations and a user-friendly experience for building real websites. However, be cautious if you’re planning to develop a complex web application, as Framer’s flexibility and control may fall short, requiring a different approach or platform.