If you are a developer building canvas applications or part of a product team needing a polished real-time collaborative environment, choose tldraw. Its infinite canvas and unique features like the "make real" turn your sketches into functional UIs, making it a solid choice for creating interactive designs. However, if you're concerned about open-source licenses or simply want a basic sketchpad, you might want to look elsewhere.
On the other hand, if you're a designer or agency focused on creating marketing sites with a robust CMS, Webflow is the better option. It gives you pixel-level control and generates clean HTML/CSS output, crucial for professional-quality websites. Just be aware that it has a steeper learning curve and costs can increase significantly with usage. If you're looking for a simple website builder or developing a complex web application, consider alternative tools.