If you’re a privacy-conscious team or an advocate for open source, choose Penpot. Its genuinely open-source nature and self-hostable options cater to those who prioritize security and control over their design tools. It’s particularly beneficial for teams looking to foster collaboration in a user-friendly environment, despite its smaller plugin ecosystem compared to more established tools.
However, if you're a developer focused on building canvas apps or need an intuitive platform for product design, go with tldraw. Its polished infinite canvas and real-time collaboration features make it ideal for turning sketches into functional UI elements. Just keep in mind that commercial use may require a paid license, so if you need a truly open-source solution, Penpot remains the better choice.